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بیماری‌های کبدی در بارداری - نسخه‌ی قابل چاپ

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بیماری‌های کبدی در بارداری - sararezaee - 07/28/2020

نقش کبد و عملکرد آن در بدن و روند بارداری
برای بررسی بیماری‌های کبدی در بارداری ابتدا به نقش و وظیفه کبد می‌پردازیم. کبد از ارگان‌های بزرگ داخل شکمی است و نقش‌های متعددی را در بدن بازی می‌کند که یکی از شناخته‌شده‌ترین آن‌ها؛ تصفیه مواد جذبی از سیستم گوارش است، چرا که تمامی موادی که توسط دستگاه گوارش، جذب خون میشوند، از کبد عبور کرده و تحت نظارت این عضو قرار می‌گیرند و به این طریق سلول‌های کبدی مواد سمی را از خون تصفیه کرده و سبب فعال شدن بسیاری از مواد شیمیایی و داروها می‌گردند. همچنین کبد نقش مهمی را در تولید انرژی، خونسازی، پروتئین‌سازی، سوخت و ساز چربی‌ها و فرآیند انعقاد خون ایفا می‌کند. با باردار شدن فرد، طیف وسیعی از تغییرات در سیستم کبدی ایجاد می‌گردد که ممکن است کبد را مستعد ابتلا به بیماری کند.
https://gahvare.net/articles/D6sBG/%D8%A8%DB%8C%D9%85%D8%A7%D8%B1%DB%8C%D9%87%D8%A7%DB%8C-%DA%A9%D8%A8%D8%AF%DB%8C-%D8%AF%D8%B1-%D8%A8%D8%A7%D8%B1%D8%AF%D8%A7%D8%B1%DB%8C
کلستاز داخل کبدی بارداری چیست؟
 زردی، یرقان یا کلستاز حاملگی Intrahepatic Cholestasis of Pregnancy(ICP) بیماری است که در آن اسیدهای صفراوی به صورت غیرطبیعی در بدن تجمع پیدا می‌کنند و باعث مشکلاتی در مادر می‌شوند. آمارهای جهانی نشان می‌دهند که، بین 1 تا 27 درصد بارداری‌ها با کلستاز داخل کبدی همراه هستند. این بیماری در فصل زمستان و بارداری‌های دو یا چندقلویی بیشتر گزارش شده است. سایر عوامل موثر در بروز بیماری کلستاز بارداری عبارتند از:
[*]ابتلا به هپاتیت C
[*]سابقه قبلی ابتلا به کلستاز داخل کبدی
[*]وجود سابقه فامیلی ابتلا به کلستاز داخل کبدی 
[*]سن بالای مادر
[*]عوامل ژنتیکی، محیطی(مثل کمبود برخی مواد معدنی و ویتامین‌ها) و هورمونی (مثل استروژن و پروژسترون) در بروز این بیماری دخیل هستند.
[*]همچنین بروز یرقان یا کلستاز در هنگام مبتلا شدن مادر به بیماری‌هایی مانند پره‌اکلامپسی (که در مقاله جداگانه به آن پرداخته‌ایم) و کبد چرب حاد بارداری نیز گزارش شده است.



RE: بیماری‌های کبدی در بارداری - Mahi01 - 11/20/2020

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RE: بیماری‌های کبدی در بارداری - Mahi01 - 11/20/2020

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